Robust and independent oversight of new strategic plan on polio eradication needed

SAGE recognized the substantial progress made by national authorities in the last 12 months in reducing transmission of wild poliovirus, particularly in northern Nigeria, northern India and many re-infected countries, but cautioned against excessive enthusiasm. Members emphasized the importance of ensuring robust and independent monitoring of major milestones of the Global Polio Eradication Initiative's new Strategic Plan for 2010-2012. They further recommended the rapid development, implementation and monitoring of corrective action in all countries in which a major milestone is seen to be at risk. SAGE recognized that insufficient financing is now the single greatest threat to polio eradication. "Recent progress suggests that interruption of transmission of poliovirus is now within our grasp." said Professor Salisbury, "It is critical that international immunization and development communities help close the US$ 1.3 billion funding gap for 2010-2012 activities so this momentum can be maintained."

SAGE supports proposal to revise WHO's vaccine prequalification procedure

SAGE expressed strong support for a proposed process to revise WHO's procedure for prequalification of vaccines, but emphasized that the quality of the service must be maintained and resources be sufficient to meet increased demand. An improved process is needed in order to better meet the challenges of the increasing volume and complexity of prequalification requests from manufacturers. Working papers have been developed on issues such as programmatic suitability of vaccines, new approaches to testing, and regulatory oversight of vaccines manufactured in multiple sites. The broad consultative process on these papers is now under way, with the proposed revisions expected to be submitted to the WHO Executive Board in May 2011 for approval.

Source: The World Health Organization