"These data highlight the need for concise, timely assessments of influenza vaccine effectiveness against the new A/H1N1 as well as seasonal strains," notes Thomas Wellems, MD, PhD, president of ASTMH. "Although the United States military constitutes a highly immunized population that may not be generalizable to civilians, it offers unique cohorts of at-risk individuals that can be studied in randomized clinical trials. We look forward to further data from this population."

"These findings suggest that while prior season's influenza vaccine may not prevent infection or developing illness once infected, it certainly appears to protect against more severe outcomes. We may also be seeing a cross-protective effect resulting from natural influenza infections and/or prior influenza immunization in the military setting," says Dr. Sanchez. "This may play a role in conferring a certain degree of 'immunological priming."

"Continued timely assessment of influenza vaccine effectiveness among military personnel is a top priority for us at the AFHSC. At the very least, our results will assist health officials in the military and Department of Defense in guiding future policy on seasonal and novel A/H1N1 vaccine use among military service members and dependents," Dr. Sanchez concludes.

SOURCE The American Society of Tropical Medicine and Hygiene