Dr. Rosenthal is a professor of microbiology, immunology and biochemistry at Northeastern Ohio Universities Colleges of Medicine and Pharmacy (NEOUCOM). He is a leading researcher in the field of herpes viruses. His research interests encompass several aspects of how herpes simplex virus (HSV) interacts with the host to cause disease. His research has addressed how HSV infects skin cells and examined viral properties that facilitate its virulence and ability to cause encephalitis. In addition, Dr. Rosenthal has also been studying a viral protein that makes the HSV more virulent by helping the virus to take over the cellular machinery to make copies of its various parts, assemble these parts together into virus particles and release the virus to infect other cells. He is also researching how the human host immune response works against HSV for the development of protective and therapeutic vaccines.

The Company has developed a library of small chemical ligands that bind to the herpes virus envelope proteins. Using these ligands, a number of candidate nanoviricides that are capable of attacking the herpes virus have been developed. The Company believes that these nanoviricide drug candidates mimic the natural, common attachment function by which HSV-1 and HSV-2 bind to the body's host cells.

The Company has previously reported that some of our nanoviricide anti-HSV drug candidates reduced HSV viral load by as much as 99.99% in certain cell culture studies.

"We are very excited about this association with the Rosenthal Lab," said Dr. Eugene Seymour, MD, MPH, CEO of the Company, adding, "We will now be able to rapidly evaluate our anti-herpes therapeutics."

SOURCE NanoViricides, Inc.