The Company has previously reported that its anti-HIV drug candidate was >25X (or >2,500%) more effective than the oral HAART treatment comprising three drugs, on a drug load basis. This study employed a standard SCID-Hu Thy/Liv mouse model. Human lymphocytes implanted in a mouse, and infected with HIV, are treated with antiviral drugs in this model. It is very important to note that no adverse events were observed in the nanoviricide treated mice, while the HAART-treated mice exhibited clinical signs of side effects. HAART or highly active anti-retroviral therapy is a three-drug combination therapy currently in use in human clinical practice, and is regarded as the most effective therapeutic regimen against HIV. If these preliminary results are confirmed in further animal studies and in human clinical trials, the Company believes that HIVCide?„? could very well result in a Functional Cure for HIV/AIDS.

The Company has reported significant progress in its topical nanoviricide eye drops program. This drug is designed to treat most viral infections of the external eye, including adenoviral epidemic kerato-conjunctivitis (EKC) and herpes keratitis.

The Company also recently reported that it has successfully added a new anti-HSV drug program to its pipeline this year. The Companys topical anti-herpes drug candidate has already demonstrated greater than 10,000-fold (>99.99%, or >4 logs) reduction in virus quantity in cell culture models of HSV-1 infection. Animal model studies of topical and genital herpes are planned.

We are now well poised to further develop our drug candidates with the objective of filing an IND application as soon as possible, said Dr. Eugene Seymour, MD, MPH, CEO of the Company.

Source: NanoViricides, Inc.